Spotlight on LATE, a newly recognized dementia subtype
As awareness grows around the many causes of cognitive decline in older adults, it is increasingly important to recognize conditions that may be confused with Alzheimer’s disease. One such condition is LATE (Limbic-predominant Age-related TDP-43 Encephalopathy).
To help clinicians, educators, caregivers, and community members better understand this emerging area of research, we are pleased to share recordings of two recent University of Washington educational presentations focused on LATE:
Geriatrics Grand Rounds
Limbic-predominant Age-related TDP-43 Encephalopathy (LATE)
Presenter: Kimiko Domoto-Reilly, MD, MS
Neurologist, Memory Brain and Wellness Center
Harborview Medical Center, UW Medicine
Date: September 4, 2026
Watch VideoThis presentation provides an overview of LATE, including its clinical features, underlying pathology, impact on cognition, and implications for clinical care in older adults. Viewers will gain insight into how LATE differs from and overlaps with other causes of dementia, including Alzheimer’s disease.
NW Geriatrics Workforce Enhancement Center Geriatric Healthcare Series
Update on Diagnosis and Therapeutics in Alzheimer’s Disease and Related Dementias
Presenter: James B. Leverenz, MD
University of Washington School of Medicine
Department of Neurology
Date: June 4, 2026
Watch VideoThis lecture explores LATE in the context of an update on Alzheimer’s disease and related dementias, discussing the evolving role of imaging biomarkers in disease characterization as well as potential disease-modifying therapeutics.